HAEMOPHILUS PARAPHROPHILUS PDF

Abstract Introduction Aggregatibacter aphrophilus formerly Haemophilus aphrophilus and H. Other infections reported in the literature include brain abscess, bone and joint infections and endophthalmitis. There are only two cases of empyema ever reported due to this organism. We report the isolation of A.

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Abstract Introduction Aggregatibacter aphrophilus formerly Haemophilus aphrophilus and H. Other infections reported in the literature include brain abscess, bone and joint infections and endophthalmitis.

There are only two cases of empyema ever reported due to this organism. We report the isolation of A. Case presentation A year-old female patient of Caucasian origin presented with a three-week history of fever, shortness of breath and dry cough. She was found to have a pleural empyema so a chest drain was inserted and a sample of pus was sent to the microbiology laboratory.

They were oxidase- and catalase-negative. It was susceptible to amoxicillin, levofloxacin and doxycycline. Our patient was treated with intravenous amoxicillin with clavulanic acid and clarithromycin followed by oral doxycycline, but was re-admitted twice over the next three months with recurrent empyema and the same organism was isolated. Each episode was managed with chest drainage and a six-week course of antibiotic--doxycycline for the second episode and amoxicillin for the third episode, after which she has remained well.

Conclusion This is the first case report of recurrent empyema due to A. Our patient had no underlying condition to explain the recurrence. Although our isolate was doxycycline susceptible, our patient had recurrent infection after treatment with this antibiotic, suggesting that this antibiotic is ineffective in treatment of deep-seated A.

This organism can be difficult to identify in the laboratory because, unlike closely related Haemophilus spp. Introduction Aggregatibacter aphrophilus formerly Haemophilus aphrophilus and H. It can be difficult to identify in the laboratory because, unlike closely related Haemophilus spp. It was first described by Khairat in when it was isolated from a patient with infective endocarditis [ 1 ]. Other infections reported in the literature include brain abscess, bone and joint infections and endophthalmitis [ 2 ].

Empyema was first described in in a patient who responded to a combination of penicillin and tetracycline [ 3 ]. A second case in more recent times was treated with amoxicillin with clavulanic acid [ 2 ]. However, resistance to cephalosporins has been described [ 4 ]. We report for the first time the isolation of A.

Case presentation A year-old female patient of Caucasian origin was admitted to our hospital with a three-week history of fever, shortness of breath and dry cough. She did not complain of hemoptysis or loss of weight, she was not a smoker and she had no history of underlying lung disorders.

On examination her temperature was An examination of her respiratory system revealed decreased breath sounds and dullness to percussion in the base of her right lung. Examination of her cardiovascular system, abdomen and central nervous system were normal. Investigations showed a white cell count of She was started on intravenous amoxicillin with clavulanic acid and clarithromycin as per hospital protocol for severe community-acquired pneumonia.

A wide bore chest drain was inserted and a sample of pus was inoculated into aerobic and anaerobic blood culture bottles. Our patient responded to intravenous amoxicillin with clavulanic acid and clarithromycin followed by oral doxycycline two weeks total antibiotic course. However she was readmitted twice over the next three months with recurrent empyema and the same organism was isolated. Each episode was managed with chest drainage and a six-week course of antibiotics; doxycycline for the second episode and amoxicillin for the third, after which she has remained well.

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